ACTIVATION OF BOVINE PERIPHERAL-BLOOD MONOCYTE AND ITS SUPPRESSIVE EFFECT ON PARASITEMIA IN THEILERIA-SERGENTI INFECTED CALVES

被引:8
作者
ISHII, M
MATSUBA, T
TAKAHASHI, K
KAWAKAMI, Y
IWAI, H
ONUMA, M
机构
[1] HOKKAIDO UNIV,FAC VET MED,DEPT EPIZOOTIOL,SAPPORO,HOKKAIDO 060,JAPAN
[2] RAKUNO GAKUEN UNIV,SCH VET MED,EBETSU 069,JAPAN
关键词
FC RECEPTOR; MONOCYTE; THEILERIA-SERGENTI;
D O I
10.1292/jvms.54.473
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Activation of bovine peripheral blood monocytes and its suppressive effect on parasite growth was examined in Theileria sergenti-infected calves by using a rosette assay that detects changes in Fc receptor expression and by luminol-dependent chemiluminescence response. Monocyte activation preceded the peak of parasitemia but was depressed parallelly with the growth of the parasites. When four calves were treated with prednisolone, three showed a good correlation between the suppression of monocyte activity and an increase of parasitemia.
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页码:473 / 477
页数:5
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