HLA ANTIGENS IN ESSENTIAL MIXED CRYOGLOBULINEMIA

被引：20

作者：

MIGLIORINI, P

BOMBARDIERI, S

CASTELLANI, A

FERRARA, GB

机构：

[1] OSPED GEN PROVINCALE, IMMUNOHEMATOL RES CTR, MASSA, ITALY

[2] UNIV PISA, RHEUMAT DIS UNIT, I-56100 PISA, ITALY

来源：

ARTHRITIS AND RHEUMATISM | 1981年 / 24卷 / 07期

关键词：

D O I：

10.1002/art.1780240711

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

HLA antigens were studied in 36 patients with essential mixed cryoglobulinemia. The antigens that showed the largest percentage of deviations from the control group were DRw3 (40% vs. 20%), DRw8 (32% vs. 11.5%) and Cw6 (5.6% vs. 20.7%). None of these changes was significant when the P values were corrected for the number of specificities scored for each locus. Essential mixed cryoglobulinemia apparently is not strongly associated with any of the HLA antigens serologically determined; certain manifestations, particularly renal involvement, may be related to a specific haplotype.

引用

页码：932 / 936

页数：5

共 22 条

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