ESTROGEN-RECEPTORS IN THE EXTERNAL ANAL-SPHINCTER

被引：37

作者：

HAADEM, K

LING, L

FERNO, M

GRAFFNER, H

机构：

[1] HOSP HELSINGBORG,DEPT SURG,S-25187 HELSINGBORG,SWEDEN

[2] UNIV LUND HOSP,DEPT ONCOL,S-22185 LUND,SWEDEN

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1991年 / 164卷 / 02期

关键词：

ANAL INCONTINENCE; ESTROGEN; ESTROGEN RECEPTORS; EXTERNAL ANAL SPHINCTER MUSCLE;

D O I：

10.1016/S0002-9378(11)80032-3

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Inasmuch as anal competence in women is reduced after the age of 50 years, it may be dependent on effects of estrogens. In this study, samples of the external anal sphincter were analyzed for the presence of estrogen receptors and were found to be present at a median concentration of 5.0 fmol per milligram of protein (range, 1.9 to 13) in women (n = 7), and 1.1 fmol per milligram of protein (range, 0 to 3.2) in men (n = 7). These findings are of interest with regard to the treatment of idiopathic anal incontinence.

引用

页码：609 / 610

页数：2