THE HUMAN GENE FOR THE ZONA-PELLUCIDA GLYCOPROTEIN ZP3 AND A 2ND POLYMORPHIC LOCUS ARE LOCATED ON CHROMOSOME-7

被引：3

作者：

VANDUIN, M ^{[1
]}

POLMAN, JEM ^{[1
]}

SUIKERBUIJK, RF ^{[1
]}

VANKESSEL, AHMG ^{[1
]}

OLIJVE, W ^{[1
]}

机构：

[1] UNIV HOSP NIJMEGEN,DEPT HUMAN GENET,NIJMEGEN,NETHERLANDS

来源：

CYTOGENETICS AND CELL GENETICS | 1993年 / 63卷 / 02期

关键词：

D O I：

10.1159/000133512

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Southern blot analysis of genomic DNA and gene-cloning experiments have recently shown that the human ZP3 gene is not a single-copy gene' The human genome harbors sequences encoding a protein of 424 amino acids and, in addition, a polymorphic locus with the potential to give rise to a probably nonfunctional polypeptide of 372 residues. In this report it is shown, by screening of a panel of human x hamster hybrid cell lines, that both the ZP3 and ZP3P loci are located on human chromosome 7.

引用

页码：111 / 113

页数：3

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