RAPID, COMPREHENSIVE SCREENING-PROCEDURE FOR BASIC DRUGS IN BLOOD OR TISSUES BY GAS-CHROMATOGRAPHY

被引：129

作者：

FOERSTER, EH ^{[1
]}

HATCHETT, D ^{[1
]}

GARRIOTT, JC ^{[1
]}

机构：

[1] SW INST FORENS SCI,TOXICOL LAB,POB 35728,DALLAS,TX 75235

来源：

JOURNAL OF ANALYTICAL TOXICOLOGY | 1978年 / 2卷 / 02期

关键词：

D O I：

10.1093/jat/2.2.50

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A method is described for the comprehensive screening and analysis of more than 80 basic compounds and metabolites in blood and other biological specimens. The method of Foerster and Mason using 1-chlorobutane as the extracting solvent with gas chromatographic analysis has been further developed and modified so that identification and quantitation of as little as 0.1 μg/ml of virtually all basic drugs in blood can be accomplished in approximately one and one-half hours.

引用

页码：50 / 55

页数：6

共 11 条

[1] TOXICOLOGICAL DETERMINATION OF BENZODIAZEPINES IN BIOLOGICAL-FLUIDS AND TISSUES BY FLAME-IONIZATION GAS-CHROMATOGRAPHY
BASELT, RC
STEWART, CB
FRANCH, SJ
[J]. JOURNAL OF ANALYTICAL TOXICOLOGY, 1977, 1 (01) : 10 - 13
[2] DiMaio V J, 1977, J Forensic Sci, V22, P152
[3] Foerster E H, 1974, J Forensic Sci, V19, P155
[4] Garriott J C, 1976, J Forensic Sci, V21, P398
[5] TOXICOLOGIC FINDINGS IN 6 FATALITIES INVOLVING METHADONE
GARRIOTT, JC
STURNER, WQ
MASON, MF
[J]. CLINICAL TOXICOLOGY, 1973, 6 (02): : 163 - 173
[6] GARRIOTT JC, 1975, METHODOLOGY ANALYTIC, V1, P121
[7] MANNO MS, 1970, J FORENSIC SCI, V15, P403
[8] QUANTITATION OF PROPOXYPHENE AND ITS MAJOR METABOLITES IN HEROIN-ADDICT PLASMA AFTER LARGE DOSE ADMINISTRATION OF PROPOXYPHENE NAPSYLATE
NASH, JF
BENNETT, IF
BOPP, RJ
BRUNSON, MK
SULLIVAN, HR
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1975, 64 (03) : 429 - 433
[9] CLINICAL AND FORENSIC EXPERIENCES WITH PHENCYCLIDINE
REYNOLDS, PC
[J]. CLINICAL TOXICOLOGY, 1976, 9 (04): : 547 - 552
[10] DETERMINATION OF PROPOXYPHENE IN HUMAN PLASMA BY GAS CHROMATOGRAPHY
WOLEN, RL
GRUBER, CM
[J]. ANALYTICAL CHEMISTRY, 1968, 40 (08) : 1243 - &

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