RADIOIMMUNOASSAY OF 17-HYDROXY-PROGESTERONE - PHYSIOLOGICAL VARIATIONS AND PATHOLOGICAL VALUES IN MAN

被引:26
作者
FIET, J [1 ]
PHAMHUUTRUNG, MT [1 ]
机构
[1] HOP TROUSSEAU,INSERM,U142,PHYSIOL ENDOCRINIENNE INFANTILE LAB,F-75571 PARIS 12,FRANCE
关键词
D O I
10.1016/0022-4731(79)90222-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Highly specific antisera, directed against 17 hydroxyprogesterone (17-OH P), were produced in rabbits. They were tested for their cross-reactivity with 29 steroids and the development of the specificity of four antisera for progesterone, 11 deoxycortisol, cortisol and 17-OH pregnenolone was followed throughout the year of immunization. Plasma 17-OH P was then determined and the values obtained from healthy adults, children and patients suffering from hirsutism and 21-hydroxylase deficiency are given. © 1979.
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页码:569 / 570
页数:2
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