EXPERIMENTAL AMEBIASIS .4. AMEBAL VIRUSES AND THE VIRULENCE OF ENTAMOEBA-HISTOLYTICA

被引：12

作者：

MATTERN, CFT ^{[1
]}

KEISTER, DB ^{[1
]}

DIAMOND, LS ^{[1
]}

机构：

[1] NIAID,PARASIT DIS LAB,BETHESDA,MD 20014

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 1979年 / 28卷 / 04期

关键词：

D O I：

10.4269/ajtmh.1979.28.653

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We have attempted to determine whether amebal viruses are capable of viral conversion of the virulence of Entamoeba histolytica. Amebae of little or no virulence for the newborn hamster liver were infected with viruses obtained from four amebal strains of different virulence. Cultures of surviving amebae were increased in virulence by viruses from amebae of high, moderate, or low virulence, but decreased in virulence by the virus of the second most pathogenic amebal strain. Sequential infection with two viruses did not produce consistent cumulative effects on virulence. The changes in virulence noted are considered to be the unpredictable result of either selection pressures exerted by the lytic virus infection or possibly viral alterations of the amebae.

引用

页码：653 / 657

页数：5

共 18 条

[1] PERSISTING BACTERIOPHAGE INFECTIONS, LYSOGENY, AND PHAGE CONVERSIONS [J].