NEURONAL DROPOUT IS GREATER IN HINDLIMB MOTOR NUCLEI THAN IN FORELIMB MOTOR NUCLEI IN AGED RATS

被引：21

作者：

HASHIZUME, K

KANDA, K

机构：

[1] TOKYO METROPOLITAN GERIATR HOSP & INST GERONTOL,DEPT PHYSIOL,35-2 SAKAECHO,ITABASHI KU,TOKYO 173,JAPAN

[2] TOKYO METROPOLITAN GERIATR HOSP & INST GERONTOL,DEPT REHABIL RES,TOKYO 173,JAPAN

来源：

NEUROSCIENCE LETTERS | 1990年 / 113卷 / 03期

关键词：

Aging; Cell survival; Forelimb; Hindlimb; Motoneuron;

D O I：

10.1016/0304-3940(90)90595-Z

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

The number of forelimb, ulnar (U) and hindlimb, medial gastrocnemius (MG) motoneurons labeled with retrograde axonal transport of horseradish peroxidase was examined in young and aged rats. No significant difference was found between the mean number of U motoneurons in young and aged rats, whereas the mean number of MG motoneurons was significantly lower in aged rats than in young rats. These results suggest that motoneuronal dropout is greater in hindlimb motor nuclei than in forelimb motor nuclei, which may contribute to differential changes in forelimb and hindlimb muscles with increasing age. © 1990.

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页码：267 / 269

页数：3

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