THE INVIVO AND INVITRO ANTI-INFLAMMATORY ACTIVITY OF CD271 - A NEW RETINOID-LIKE MODULATOR OF CELL-DIFFERENTIATION

被引：33

作者：

HENSBY, C ^{[1
]}

CAVEY, D ^{[1
]}

BOUCLIER, M ^{[1
]}

CHATELUS, A ^{[1
]}

ALGATE, D ^{[1
]}

EUSTACHE, J ^{[1
]}

SHROOT, B ^{[1
]}

机构：

[1] HUNTINGDON RES CTR,DEPT PHARMACOL,HUNTINGDON PE18 6ES,CAMBS,ENGLAND

来源：

AGENTS AND ACTIONS | 1990年 / 29卷 / 1-2期

关键词：

D O I：

10.1007/BF01964720

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

CD 271 possesses a potent anti- inflammatory activity in a large number of models particularly when compared with known reference anti-inflammatory agents. Retinoids (all-trans retinoic acid, 13 cis retinoic acid and Etretinate) show very weak or no activity. In view of these properties of CD 271, an enhanced therapeutic value can be anticipated in the treatment of skin diseases such as acne and psoriasis. © 1990 Birkhäuser Verlag.

引用

页码：56 / 58

页数：3