AN EFFICIENT AND FACILE SYNTHESIS OF NOVEL 2-ARYLPYRIDO[2,3-D]PYRIMIDIN-5(8H)-ONES

被引：7

作者：

SINGH, B

LASKOWSKI, SC

LESHER, GY

机构：

[1] Department of Medicinal Chemistry, Sterling Research Group, Rensselaer, 12144, NY

来源：

SYNLETT | 1990年 / 09期

关键词：

D O I：

10.1055/s-1990-21163

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Thermolysis of pyrimidinylaminomethylene derivatives 3 of Meldrum's acid (2,2-dimethyl-1,3-dioxane-4,6-dione) produced 2-arylpyrido[2,3-d]pyrimidin-5(8H)-ones 4 in moderate to excellent yield. © 1990 Georg Thieme Verlag. All rights reserved.

引用

页码：549 / 550

页数：2

共 6 条

[1]

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[2]

CASSIS R, 1985, SYNTHETIC COMMUN, V5, P125

[3] THERMAL FUNCTIONALIZATION OF NITROGEN SUBSTITUENTS - FORMATION OF DIHYDROPYRROL-3-ONES, QUINOLIN-4-ONES, AND ENAMINOENAMINONES BY GAS-PHASE HYDROGEN TRANSFER-REACTIONS [J].

GORDON, HJ ;

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JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1983, (17) :957-958

[4]

NISHIGAKI S, 1970, CHEM PHARM BULL, V18, P1385

[5] 3 CONVENIENT AND NOVEL SYNTHESES OF 4-AMINO-2-ARYLPYRIMIDINES [J].

SINGH, B ;

LESHER, GY .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1977, 14 (08) :1413-1414

[6] SYNTHESIS OF 5,8-DIHYDRO-5-OXO-2-(3-PYRIDINYL OR 4-PYRIDINYL)-PYRIDO[2,3-D]PYRIMIDINE-6-CARBOXYLIC ACIDS AND THE REINVESTIGATION OF THE THERMAL CYCLIZATION OF DIETHYL (2-HYDROXY-4-PYRIMIDINYL)AMINO-METHYLENEMALONATE [J].

SINGH, B ;

LESHER, GY .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1982, 19 (06) :1581-1582

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