学术探索
学术期刊
新闻热点
数据分析
智能评审

MECHANISMS OF ACTION OF BIOCIDES

被引：85
作者：
DENYER, SP
机构：
[1] Department of Pharmaceutical Sciences, University of Nottingham, Nottingham, NG7 2RD, University Park
来源：
INTERNATIONAL BIODETERIORATION | 1990年 / 26卷 / 2-4期
关键词：
D O I：
10.1016/0265-3036(90)90050-H
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Detailed studies have clearly demonstrated that few biocides can be considered now as general cell poisons. Biocidal action may result through physicochemical interaction with microbial target structures, specific reactions with biological molecules, or disturbance of selected metabolic or energetic processes. Mechanism of action studies, if intelligently applied, can provide direction to the development of novel biocides and biocidal systems. © 1990.
引用
收藏
页码：89 / 100
页数：12
相关论文
共 57 条
  • [1] Bloomfield, The effect of the phenolic antibacterial agent Fentichlor on energy coupling in Staphylococcus aureus, Journal of Applied Bacteriology, 37, pp. 117-131, (1974)
  • [2] Broxton, Woodcock, Gilbert, A study of the antibacterial activity of some polyhexamethylene biguanides towards Escherichia coli ATCC 8739, Journal of Applied Bacteriology, 54, pp. 345-353, (1983)
  • [3] Chawner, Gilbert, A comparative study of the bactericidal and growth inhibitory activities of the bisbiguanide alexidine and chlorhexidine, Journal of Applied Bacteriology, 66, pp. 243-252, (1989)
  • [4] Corner, Synergism in the inhibition of Bacillus subtilis by combinations of lipophilic weak acids and fatty alcohols, Antimicrobial Agents and Chemotherapy, 19, pp. 1082-1095, (1981)
  • [5] Davies, Field, Action of biguanides, phenol and detergents on Escherichia coli and its spheroplasts, Journal of Applied Bacteriology, 32, pp. 233-243, (1969)
  • [6] Denyer, King, Development of preservative systems, Microbial Quality Assurance in Pharmaceuticals, Cosmetics and Toiletries, pp. 156-170, (1988)
  • [7] Denyer, Hugo, Witham, The antibacterial action of a series of 4-n-alkylphenols, Journal of Pharmacy and Pharmacology, 32, (1980)
  • [8] Denyer, Harding, Hugo, The mechanism of bacteriostatic action of chlorocresol (CC) on Staphylococcus aureas, Journal of Pharmacy and Pharmacology, 37, (1985)
  • [9] Denyer, Hugo, Harding, The biochemical basis of synergy between the antibacterial agents chlorocresol and 2-phenylethanol, International Journal of Pharmaceutics, 29, pp. 29-36, (1986)
  • [10] Denyer, Jackson, Al-Sagher, Intracellular delivery of biocides, Mechanisms of Action of Chemical Biocides: their Study and Exploitation, SAB Technical Series 27, (1990)
123456