DEPRESSOR EFFECT OF TANNIN IN GREEN TEA ON RATS WITH RENAL-HYPERTENSION

The effects of green tea tannin on blood pressure were examined for rats with adenine-induced hypertension and renal failure. The systolic, mean, and diastolic blood pressure values were decreased by green tea tannin administration, whereas the urinary levels of kallikrein, prostaglandin E(2), and sodium were increased. No remarkable change was observed in the plasma renin activity. The angiotensin II and aldosterone levels were also unchanged in rats to which green tea tannin was administered. The mechanism for the depressor action of green tea tannin is discussed on the basis of these findings.