INSULIN AND GLUCAGON-LEVELS IN FULMINANT HEPATIC-FAILURE IN MAN

被引：17

作者：

FIACCADORI, F

PEDRETTI, G

FERRARI, C

PIZZAFERRI, P

RIGGIO, O

ORLANDI, N

PEZZAROSSA, A

机构：

[1] UNIV PARMA,DEPT ENDOCRINOL,I-43100 PARMA,ITALY

[2] UNIV ROME LA SAPIENZA,DEPT GASTROENTEROL 2,I-00185 ROME,ITALY

来源：

DIGESTIVE DISEASES AND SCIENCES | 1991年 / 36卷 / 06期

关键词：

FULMINANT HEPATIC FAILURE; PANCREATIC HORMONES; NEUTRAL AMINO ACIDS; HEPATIC REGENERATION;

D O I：

10.1007/BF01311240

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The behavior of insulin and glucagon and related metabolic substrates was assayed in plasma of patients with fulminant hepatic failure. All 12 subjects were provided the same nutritional support. High levels of insulin and glucagon were present at all times and no difference was observed between surviving patients (four) and those who died (8). Elevated values for branched-chain and aromatic amino acids as well as alanine were present. Statistically significant lower levels of aromatic amino acids and consequently a greater branched chain-aromatic amino acid ratio was found in surviving vs nonsurviving patients. A significantly greater level of alpha-fetoprotein was found in patients who survived as compared to those who died.

引用

页码：801 / 808

页数：8

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