INTRATHECAL IMMUNOGLOBULIN-SYNTHESIS - COMPARISON OF VARIOUS FORMULAS WITH THE GOLD STANDARD OF ISOELECTRIC-FOCUSING

被引：27

作者：

SOUVERIJN, JHM ^{[1
]}

SERREE, HMP ^{[1
]}

PEET, R ^{[1
]}

SMIT, WG ^{[1
]}

BRUYN, GW ^{[1
]}

机构：

[1] STATE UNIV LEIDEN HOSP,DEPT NEUROL,2333 AA LEIDEN,NETHERLANDS

来源：

JOURNAL OF THE NEUROLOGICAL SCIENCES | 1991年 / 102卷 / 01期

关键词：

INTRATHECAL IG SYNTHESIS; CEREBROSPINAL FLUID; ISOELECTRIC FOCUSING; ROC CURVE; CALCULATION FORMULA;

D O I：

10.1016/0022-510X(91)90087-N

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The recent introduction of a further new formula for calculating intrathecal Ig synthesis led us to compare the results of calculations obtained when using it and certain other older formulae with those of isoelectric focusing (IEF), since only the latter proves the intrathecal synthesis of oligoclonal proteins. On comparison, it was found that the results produced by the usual formulae were, without exception, inferior to those of isoelectric focusing. By using Receiver Operating Characteristic (ROC) curves, it is shown that calculations with the Reiber formula agree best with IEF. Virtually the same results are obtained with the "In IgG index + 1" and "IgG index".

引用

页码：11 / 16

页数：6

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