THE LANDAU-KLEFFNER SYNDROME OR ACQUIRED APHASIA WITH CONVULSIVE DISORDER - LONG-TERM FOLLOW-UP OF 6 CHILDREN AND A REVIEW OF THE RECENT LITERATURE

被引:123
作者
PAQUIER, PF
VANDONGEN, HR
LOONEN, CB
机构
[1] ERASMUS UNIV,HOSP DIJKZIGT,DEPT NEUROL,ROOM EE 2287,POB 1738,3000 DR ROTTERDAM,NETHERLANDS
[2] UNIV HOSP ANTWERP,DEPT NEUROL,DIV NEUROLINGUIST,ANTWERP,BELGIUM
[3] UNIV HOSP ANTWERP,DEPT EAR NOSE & THROAT SURG,ANTWERP,BELGIUM
关键词
D O I
10.1001/archneur.1992.00530280034019
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We present six patients with acquired aphasia with convulsive disorder (Landau-Kleffner syndrome) and distill the main clinical features from a review of the recent literature. Our series showed that the clinical picture can vary at onset, as well as during the course of the illness, and that the long-term outcome of the aphasia is quite unpredictable, despite the fact that epilepsy and electroencephalographic abnormalities usually regress or disappear with the years. We also call attention to the electroencephalographic phenomenon of electrical status epilepticus during slow sleep, and we suggest that the course of the aphasia may well be linked to the appearance and disappearance of electrical status epilepticus during slow sleep. Therefore, we recommend a sleep electroencephalogram in all children with Landau-Kleffner syndrome. Finally, our findings did not demonstrate the beneficial effect of treatment with anticonvulsants on the aphasia, but recent studies have shown that treatment with corticosteroids, whether combined with anticonvulsants, is effective.
引用
收藏
页码:354 / 359
页数:6
相关论文
共 58 条
  • [1] ANDREWS R, 1989, ANN NEUROL, V26, P469
  • [2] THE LANDAU-KLEFFNER SYNDROME - CASE-REPORT AND THEORETICAL CONSIDERATIONS
    ANSINK, BJJ
    SARPHATIE, H
    VANDONGEN, HR
    [J]. NEUROPEDIATRICS, 1989, 20 (03) : 170 - 172
  • [3] BHATIA M S, 1988, Indian Journal of Pediatrics, V55, P987, DOI 10.1007/BF02727844
  • [4] Billard C, 1982, SLEEP EPILEPSY, P481
  • [5] Billard C, 1991, ANAE, V3, P39
  • [6] BISHOP DVM, 1985, DEV MED CHILD NEUROL, V27, P705
  • [7] CONTINUOUS SPIKES AND WAVES DURING SLOW SLEEP - A 30 MONTHS FOLLOW-UP-STUDY OF NEUROPSYCHOLOGICAL RECOVERY AND EEG FINDINGS
    BOEL, M
    CASAER, P
    [J]. NEUROPEDIATRICS, 1989, 20 (03) : 176 - 180
  • [8] THE LANDAU-KLEFFNER SYNDROME OF ACQUIRED EPILEPTIC APHASIA - UNUSUAL CLINICAL OUTCOME, SURGICAL EXPERIENCE, AND ABSENCE OF ENCEPHALITIS
    COLE, AJ
    ANDERMANN, F
    TAYLOR, L
    OLIVIER, A
    RASMUSSEN, T
    ROBITAILLE, Y
    SPIRE, JP
    [J]. NEUROLOGY, 1988, 38 (01) : 31 - 38
  • [9] ACQUIRED AUDITORY VERBAL AGNOSIA AND SEIZURES IN CHILDHOOD
    COOPER, JA
    FERRY, PC
    [J]. JOURNAL OF SPEECH AND HEARING DISORDERS, 1978, 43 (02): : 176 - 184
  • [10] DEANNA TW, 1991, J CLIN NEUROPHYSIOL, V7, P288