MEMBRANE GLYCOLIPIDS - REGIONAL SYNTHESIS AND AXONAL-TRANSPORT IN A SINGLE IDENTIFIED NEURON OF APLYSIA-CALIFORNICA

被引：36

作者：

SHERBANY, AA

AMBRON, RT

SCHWARTZ, JH

机构：

来源：

SCIENCE | 1979年 / 203卷 / 4375期

关键词：

D O I：

10.1126/science.83001

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Glycolipids moving along an identified axon of Aplysia californica were synthesized and incorporated into intracytoplasmic membranes solely in the perikaryon: direct injection of tritiated sugar into the axon revealed no local synthesis or exchange. There was no indication for transfer into axoplasm from glia. Insertion of glycolipids into nascent membranes occurs coordinately with insertion of protein components in the cell body. Copyright © 1978 AAAS.

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页码：78 / 81

页数：4

相关论文

共 43 条

[1] RAPID TRANSPORT OF PHOSPHATIDYLCHOLINE OCCURRING SIMULTANEOUSLY WITH PROTEIN TRANSPORT IN FROG SCIATIC-NERVE [J].

ABE, T ;

HAGA, T ;

KUROKAWA, M .

BIOCHEMICAL JOURNAL, 1973, 136 (03) :731-740

[2] EFFECT OF INHIBITING PROTEIN-SYNTHESIS ON AXONAL-TRANSPORT OF MEMBRANE GLYCOPROTEINS IN AN IDENTIFIED NEURON OF APLYSIA [J].

AMBRON, RT ;

GOLDMAN, JE ;

SCHWARTZ, JH .

BRAIN RESEARCH, 1975, 94 (02) :307-323

[3] GLYCOPROTEINS ARE MODIFIED IN AXON OF R2, GIANT NEURON OF APLYSIA-CALIFORNICA, AFTER INTRA-AXONAL INJECTION OF [N-ACETYLGALACTOSAMINE-H-3 [J].

AMBRON, RT ;

TREISTMAN, SN .

BRAIN RESEARCH, 1977, 121 (02) :287-309

[4] AXONAL-TRANSPORT OF NEWLY SYNTHESIZED GLYCOPROTEINS IN A SINGLE IDENTIFIED NEURON OF APLYSIA-CALIFORNICA [J].

AMBRON, RT ;

GOLDMAN, JE ;

SCHWARTZ, JH .

JOURNAL OF CELL BIOLOGY, 1974, 61 (03) :665-675

[5] SYNTHESIS OF GLYCOPROTEINS IN A SINGLE IDENTIFIED NEURON OF APLYSIA-CALIFORNICA [J].

AMBRON, RT ;

GOLDMAN, JE ;

THOMPSON, EB ;

SCHWARTZ, JH .

JOURNAL OF CELL BIOLOGY, 1974, 61 (03) :649-664

[6] SYNAPTIC MACROMOLECULES - IDENTIFICATION AND METABOLISM [J].

BARONDES, SH .

ANNUAL REVIEW OF BIOCHEMISTRY, 1974, 43 :147-168

[7] ULTRASTRUCTURAL LOCALIZATION OF PHOSPHOLIPID SYNTHESIS IN RAT TRIGEMINAL NERVE DURING MYELINATION [J].

BENES, F ;

HIGGINS, JA ;

BARRNETT, RJ .

JOURNAL OF CELL BIOLOGY, 1973, 57 (03) :613-629

[8] AXONAL-TRANSPORT AND AXONAL PROCESSING OF LOW-MOLECULAR WEIGHT PROTEINS FROM ABDOMINAL-GANGLION OF APLYSIA [J].

BERRY, RW ;

SCHWARTZ, AW .

BRAIN RESEARCH, 1977, 129 (01) :75-90

[9]

CHIEN JL, 1973, J BIOL CHEM, V248, P1778

[10]

CZICHI U, 1977, J BIOL CHEM, V252, P7901

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