OVINE COCCIDIOSIS - THE PATHOLOGY OF EIMERIA-CRANDALLIS INFECTION

被引:30
作者
GREGORY, MW [1 ]
CATCHPOLE, J [1 ]
机构
[1] MAFF,CENT VET LAB,WEYBRIDGE KT15 3NB,SURREY,ENGLAND
关键词
Coccidiosis; crypt atrophy; diarrhoea; Eimeria crandallis; enteritis; enteropathy; intestine; lambs; pathology; sheep;
D O I
10.1016/0020-7519(90)90022-F
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Doses of sporulated oocysts of Eimeria crandallis ranging from 50 to 300,000,000 were given to 27 housed lambs aged between 4 and 12 weeks that had been reared coccidia-free. Lambs were killed between 1 and 22 days after inoculation and their tissues examined histologically. Clinical effects were very variable and not closely related to inoculating dose. Some lambs showed intermittent diarrhoea, sometimes watery and sometimes containing muco-fibrinous material, either in the form of intestinal casts or as a greyish discoloration. Loss of surface epithelial cells and villus atrophy in the small intestine were associated with first generation meronts and the release of merozoites from them; in some lambs apoptosis of crypt cells also occurred, leading to crypt atrophy. Severe diffuse crypt hyperplasia was associated with pro-gamonts in the small and large intestines. In a minority of the lambs this stage was associated with what appeared to be crypt destruction by host cells in the lamina propria, leading in some cases to denudation and severe diarrhoea. © 1990.
引用
收藏
页码:849 / 860
页数:12
相关论文
共 22 条
[1]   PATHOGENICITY OF THE COCCIDIUM EIMERIA-CRANDALLIS IN LABORATORY LAMBS [J].
CATCHPOLE, J ;
GREGORY, MW .
PARASITOLOGY, 1985, 91 (AUG) :45-52
[2]   EXPERIMENTS WITH DEFINED MULTISPECIFIC COCCIDIAL INFECTIONS IN LAMBS [J].
CATCHPOLE, J ;
NORTON, CC ;
JOYNER, LP .
PARASITOLOGY, 1976, 72 (APR) :137-147
[3]   DEATH AND THE CELL [J].
DUVALL, E ;
WYLLIE, AH .
IMMUNOLOGY TODAY, 1986, 7 (04) :115-119
[4]  
FERNANDO MA, 1983, EXP PARASITOL, V56, P20, DOI 10.1016/0014-4894(83)90093-0
[5]  
GJERDE B, 1987, ACTA VET SCAND, V28, P33
[6]   OVINE COCCIDIOSIS - OBSERVATIONS ON OOCYST PATCHES AND POLYPS IN NATURALLY-ACQUIRED INFECTIONS [J].
GREGORY, MW ;
CATCHPOLE, J ;
PITTILO, RM ;
NORTON, CC .
INTERNATIONAL JOURNAL FOR PARASITOLOGY, 1987, 17 (06) :1113-1124
[7]   A NEW COCCIDIAL STAGE [J].
GREGORY, MW ;
CATCHPOLE, J ;
NORTON, CC ;
PITTILO, RM .
VETERINARY RECORD, 1987, 121 (16) :383-383
[8]   OVINE COCCIDIOSIS IN ENGLAND AND WALES 1978-1979 [J].
GREGORY, MW ;
JOYNER, LP ;
CATCHPOLE, J ;
NORTON, CC .
VETERINARY RECORD, 1980, 106 (22) :461-462
[9]   OBSERVATIONS ON THE ENDOGENOUS STAGES OF EIMERIA-CRANDALLIS IN DOMESTIC LAMBS (OVIS-ARIES) [J].
GREGORY, MW ;
CATCHPOLE, J ;
NORTON, CC .
INTERNATIONAL JOURNAL FOR PARASITOLOGY, 1989, 19 (08) :907-914
[10]   OVINE COCCIDIOSIS - PATHOLOGY OF EIMERIA-OVINOIDALIS INFECTION [J].
GREGORY, MW ;
CATCHPOLE, J .
INTERNATIONAL JOURNAL FOR PARASITOLOGY, 1987, 17 (06) :1099-1111