ACTION OF PROSTACYCLIN (PGI2) ON THE CONTRACTILITY OF THE ISOLATED CIRCULAR AND LONGITUDINAL MUSCLE LAYERS OF THE HUMAN OVIDUCT

被引：18

作者：

LINDBLOM, B

WILHELMSSON, L

WIQVIST, N

机构：

[1] Department of Obstetrics, Gynecology University of Göteborg

来源：

PROSTAGLANDINS | 1979年 / 17卷 / 01期

关键词：

D O I：

10.1016/0090-6980(79)90079-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Small strips from the circular and longitudinal muscle layers of the ampullary-isthmic portion of the human oviduct were mounted in organ chambers for recording of their spontaneous contractility. Concentrations in the order of 1-300 ng/ml of PGI2 were tested and compared with similar concentrations of PGE2 and PGF2α. It was found that PGI2 contracted the longitudinal muscle layer in the same manner as did PGE2. The spontaneous activity of the circular layer was markedly suppressed by PGE2 but only moderately inhibited by PGI2 even at high concentrations. © 1979.

引用

页码：99 / 104

页数：6

共 9 条

[1]

COUTINHO EM, 1971, FERTIL STERIL, V22, P539

[2] PRODUCTION OF PROSTAGLANDINS BY PSEUDOPREGNANT RAT UTERUS, INVITRO, AND EFFECT OF TAMOXIFEN WITH IDENTIFICATION OF 6-KETO-PROSTAGLANDIN-F1ALPHA AS A MAJOR PRODUCT [J].