ARYL-SUBSTITUTED CYCLOHEXADIENYL COMPLEXES - NOVEL INTERMEDIATES FOR AN ORGANOMETALLIC APPROACH TO SCELETIUM AND AMARYLLIDACEAE ALKALOID SYNTHESIS

被引：35

作者：

OWEN, DA ^{[1
]}

STEPHENSON, GR ^{[1
]}

FINCH, H ^{[1
]}

SWANSON, S ^{[1
]}

机构：

[1] GLAXO GRP RES LTD,WARE SG12 0DJ,HERTS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 24期

关键词：

D O I：

10.1016/S0040-4039(00)97407-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new method for the synthesis of 1-phenyl substituted tricarbonyl(π5-cyclohexadienyl)iron(l+) complexes is described. Although 1-phenyl substituents were found to direct nucleophiles to the far end of the β-system, this effect could be overcome by a methoxyl substituent at C-4, permitting a regio- and stereocontrolled alkylation step that forms a quaternary centre required in Sceletium and Amaryllidaceae alkaloid synthesis. © 1990.

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页码：3401 / 3404

页数：4

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