TRANSDERMAL CLONIDINE FOR AMELIORATING POSTORCHIECTOMY HOT FLASHES

被引：65

作者：

LOPRINZI, CL

GOLDBERG, RM

OFALLON, JR

QUELLA, SK

MISER, AW

MYNDERSE, LA

BROWN, LD

TSCHETTER, LK

WILWERDING, MB

DOSE, AM

OESTERLING, JE

机构：

[1] MAYO CLIN & MAYO FDN,DEPT UROL,ROCHESTER,MN 55905

[2] GEISINGER MED CTR,CLIN ONCOL PROGRAM,DANVILLE,PA

[3] IOWA ONCOL RES ASSOC,COMMUNITY CLIN ONCOL PROGRAM,DES MOINES,IA

[4] SIOUX COMMUNITY CANC CONSORTIUM,SIOUX FALLS,SD

[5] UNIV NEBRASKA,CREIGHTON UNIV,MED CTR & ASSOCIATES,NEBRASKA ONCOL GRP,OMAHA,NE

来源：

JOURNAL OF UROLOGY | 1994年 / 151卷 / 03期

关键词：

PROSTATIC NEOPLASMS; ORCHIECTOMY; CLONIDINE; FLUSHING;

D O I：

10.1016/S0022-5347(17)35034-6

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

To determine the efficacy of transdermal clonidine for alleviating post-orchiectomy hot flashes, a randomized, double-blind, crossover clinical trial was designed including 70 men with a history of prostate cancer who had undergone a medical or surgical orchiectomy and were suffering from hot flashes. The results of this study demonstrated that clonidine did not significantly decrease hot flash frequency or severity. Future research is necessary to find effective means of alleviating hot flashes in post-orchiectomy patients.

引用

页码：634 / 636

页数：3

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