5-(3-HYDROXYMETHYL-3-METHYL-1-TRIAZENO IMIDAZOLE-4-CARBOXAMIDE IS A METABOLITE OF 5-(3,3-DIMETHYL-1-TRIAZENO)IMIDAZOLE-4-CARBOXAMIDE (DIC,DTIC NSC-45388)

被引：44

作者：

KOLAR, GF

MAURER, M

WILDSCHUTTE, M

机构：

来源：

CANCER LETTERS | 1980年 / 10卷 / 03期

关键词：

D O I：

10.1016/0304-3835(80)90076-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：235 / 241

页数：7

共 15 条

[1]

COMIS RL, 1976, CANCER TREAT REP, V60, P165

[2] TUMOR INHIBITORY TRIAZENES - STRUCTURAL REQUIREMENTS FOR AN ACTIVE METABOLITE [J].

CONNORS, TA ;

GODDARD, PM ;

MERAI, K ;

ROSS, WCJ ;

WILMAN, DEV .

BIOCHEMICAL PHARMACOLOGY, 1976, 25 (03) :241-246

[3]

GESCHER A, 1978, TETRAHEDRON LETT, P5041

[4]

GOTTLIEB JA, 1976, CANCER TREAT REP, V60, P199

[5] INVESTIGATION OF THE MECHANISM OF ACTION OF ANTITUMOUR DIMETHYLTRIAZENES [J].

HICKMAN, JA .

BIOCHIMIE, 1978, 60 (09) :997-1002

[6] ELEVATED URINARY EXCRETION OF 4-AMINOIMIDAZOLE-5-CARBOXAMIDE IN PATIENTS AFTER INTRAVENOUS INJECTION OF 4-(3,3-DIMETHYL-1-TRIAZENO)IMIDAZOLE-5-CARBOXAMIDE [J].

HOUSHOLDER, GE ;

LOO, TL .

LIFE SCIENCES PART 1 PHYSIOLOGY AND PHARMACOLOGY AND PART 2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY, 1969, 8 (9P1) :533-+

[7]

HOUSHOLDER GE, 1971, J PHARMACOL EXP THER, V179, P386

[8] URINARY METABOLITE OF 1-(2,4,6-TRICHLOROPHENYL)-3,3-DIMETHYLTRIAZENE WITH AN INTACT DIAZOAMINO STRUCTURE [J].

KOLAR, GF ;

CARUBELLI, R .

CANCER LETTERS, 1979, 7 (04) :209-214

[9] URINARY METABOLITES OF 3,3-DIMETHYL-1-PHENYLTRIAZENE [J].

KOLAR, GF ;

SCHLESIGER, J .

CHEMICO-BIOLOGICAL INTERACTIONS, 1976, 14 (3-4) :301-311

[10]

KOLAR GF, 1979, GLYCOCONJUGATES, P656

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