HEPATOCYTE NUCLEAR FACTOR 3/FORK HEAD OR WINGED HELIX PROTEINS - A FAMILY OF TRANSCRIPTION FACTORS OF DIVERSE BIOLOGIC FUNCTION

被引：315

作者：

LAI, E

CLARK, KL

BURLEY, SK

DARNELL, JE

机构：

[1] MEM SLOAN KETTERING CANC CTR,DEPT MED,NEW YORK,NY 10021

[2] ROCKEFELLER UNIV,HOWARD HUGHES MED INST,MOLEC BIOPHYS LABS,NEW YORK,NY 10021

[3] ROCKEFELLER UNIV,MOLEC CELL BIOL LAB,NEW YORK,NY 10021

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1993年 / 90卷 / 22期

关键词：

D O I：

10.1073/pnas.90.22.10421

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A family of transcription factors, first identified as hepatocyte nuclear factors (HNF-3alpha, -3beta, and -3gamma) and as a homeotic Drosophila mutant, fork head, has been intensively studied for the past 4 years. Important findings have emerged about the structure of the DNA-binding portion of the proteins as well as biologic discoveries about the diversity of the family and its implied role in early development.

引用

页码：10421 / 10423

页数：3

共 23 条

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