SYNTHESIS OF 3-AMINORHODANINE DERIVATIVES AS ALDOSE REDUCTASE INHIBITORS

被引：13

作者：

HANEFELD, W

SCHLITZER, M

机构：

[1] Institut Für Pharmazeutische Chemie, Marburg, D-35032

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1995年 / 32卷 / 03期

关键词：

D O I：

10.1002/jhet.5570320358

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A number of 5-condensated 3-acylaminorhodanines 3 was prepared as potential inhibitors of the aldose reductase by acylation of the amino group of 3-aminorhodanine 1 and subsequent condensation of the 5-methylene function with appropriate aldehydes. Some of these compounds displayed interesting activity.

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页码：1019 / 1025

页数：7

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