TETRACYCLIC TRITERPENOIDS OF THE FRUIT COATS OF AZADIRACHTA-INDICA

被引：20

作者：

SIDDIQUI, S ^{[1
]}

SIDDIQUI, BS ^{[1
]}

GHIASUDDIN ^{[1
]}

FAIZI, S ^{[1
]}

机构：

[1] UNIV KARACHI, HEJ RES INST CHEM, KARACHI 75270, PAKISTAN

来源：

JOURNAL OF NATURAL PRODUCTS | 1991年 / 54卷 / 02期

关键词：

D O I：

10.1021/np50074a010

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

From the EtOH extract of the coats of fresh, undried, uncrushed, ripe fruits of neem, Azadirachta indica, a new tetracyclic triterpenoid azadirol {1} and a known triterpenoid, kulactone {5}, hitherto unreported from neem, have been isolated. Their structures have been elucidated through spectroscopic methods and chemical transformations. Azadirol {1} is the first naturally occurring apotirucallol (apoeuphol) derivative with the C-8 side chain uncyclized and represents an immediate intermediate in the biosynthesis from tirucallol (euphol) of apotirucallol (apoeuphol) triterpenoids with a degraded or cyclized side chain.

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页码：408 / 415

页数：8

相关论文

共 27 条

[1]

TRICYCLIC DITERPENOIDS FROM THE STEM BARK OF AZADIRACHTA-INDICA [J].

ARA, I ;

SIDDIQUI, BS ;

FAIZI, S ;

SIDDIQUI, S .

JOURNAL OF NATURAL PRODUCTS, 1988, 51 (06) :1054-1061

[2]

THE CONSTITUTION OF LIMONIN [J].

ARIGONI, D ;

BARTON, DHR ;

COREY, EJ ;

JEGER, O ;

CAGLIOTI, L ;

DEV, S ;

FERRINI, PG ;

GLAZIER, ER ;

MELERA, A ;

PRADHAN, SK ;

SCHAFFNER, K ;

STERNHELL, S ;

TEMPLETON, JF ;

TOBINAGA, S .

EXPERIENTIA, 1960, 16 (02) :41-49

[3]

TRITERPENES FROM SIMABA-MULTIFLORA [J].

ARISAWA, M ;

FUJITA, A ;

MORITA, N ;

COX, PJ ;

HOWIE, RA ;

CORDELL, GA .

PHYTOCHEMISTRY, 1987, 26 (12) :3301-3303

[4]

IDENTIFICATION OF 24-METHYLENELOPHENOL FROM HEARTWOOD OF AZADIRACHTA-INDICA [J].

BANERJI, R ;

MISRA, G ;

NIGAM, SK .

PHYTOCHEMISTRY, 1987, 26 (09) :2644-2645

[5]

TETRACYCLIC TRITERPENOIDS FROM MELIA-AZEDARACH, L-III [J].

CHIANG, CK ;

CHANG, FC .

TETRAHEDRON, 1973, 29 (14) :1911-1929

[6]

Chopra R. N., 1956, GLOSSARY INDIAN MED, P31

[7]

THE APPLICATION OF VACUUM LIQUID-CHROMATOGRAPHY TO THE SEPARATION OF TERPENE MIXTURES [J].

COLL, JC ;

BOWDEN, BF .

JOURNAL OF NATURAL PRODUCTS, 1986, 49 (05) :934-936

[8]

TETRANORTRITERPENOIDS AND RELATED SUBSTANCES .13. CONSTITUTION OF GRANDIFOLIOLENONE, AN APO-TIRUCALLOL DERIVATIVE FROM KHAYA-GRANDIFOLIOLA(MELIACEAE) [J].

CONNOLLY, JD ;

MCCRINDLE, R .

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1971, (09) :1715-+

[9]

DYMOCK W, 1890, PHARMACOGRAPHIA INDI, V1, P322

[10]

DETERMINATION OF ABSOLUTE CONFIGURATION OF HYDROXYLATED SESQUITERPENE LACTONES BY HOREAUS METHOD OF ASYMMETRIC ESTERIFICATION [J].

HERZ, W ;

KAGAN, HB .

JOURNAL OF ORGANIC CHEMISTRY, 1967, 32 (01) :216-&