DEVELOPMENTAL ASPECTS OF RAT-HEART MONO-AMINE OXIDASE

被引:24
作者
EDWARDS, DJ
PAK, KY
VENETTI, MC
机构
[1] Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh
关键词
D O I
10.1016/0006-2952(79)90697-X
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Rat heart mitochondria were demonstrated to contain two forms of monoamine oxidase which resemble the A and B forms found in other tissues on the basis of the effects of clorgyline, thermostability, and kinetic characteristics. The relative amounts of these two enzyme forms underwent a marked change between 3 and 15 weeks of age. In the adult, only the form resembling type A MAO could be demonstrated. © 1979.
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页码:2337 / 2343
页数:7
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