ACTIVITY OF RIFAMPIN PLUS TRIMETHOPRIM AGAINST HEMOPHILUS-INFLUENZAE

被引：7

作者：

BERTI, M

SCOTTI, R

RIPAMONTI, F

ARIOLI, V

机构：

[1] Chemotherapy Department, Gruppo Lepetit SpA, Milano, I-20158, Via G. Durando

来源：

CURRENT MICROBIOLOGY | 1979年 / 2卷 / 04期

关键词：

D O I：

10.1007/BF02601717

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The activity of the combination rifampin plus trimethoprim against Haemophilus influenzae was studied from the point of view of synergism, bactericidal activity, and inhibition of the selection of rifampin-resistant cells. At concentrations of the two drugs that are easily attainable in human serum after oral treatment with 600 mg of rifampin plus 160 mg of trimethoprim, the combination acted synergistically on all of the strains tested, was remarkably bactericidal, and inhibited the selection of rifampin-resistant cells. © 1979 Springer-Veralg New York Inc.

引用

页码：223 / 225

页数：3

共 14 条

[1]

Acocella G, 1976, J Antimicrob Chemother, V2, P271, DOI 10.1093/jac/2.3.271

[2]

ARIOLI V, 1967, ARZNEI-FORSCHUNG, V17, P523

[3] INTERACTION BETWEEN RIFAMPICIN AND TRIMETHOPRIM INVITRO AND IN EXPERIMENTAL INFECTIONS [J].