MECHANISMS OF INSULIN RESISTANCE IN HUMAN OBESITY - EVIDENCE FOR RECEPTOR AND POSTRECEPTOR DEFECTS

被引：621

作者：

KOLTERMAN, OG ^{[1
]}

INSEL, J ^{[1
]}

SAEKOW, M ^{[1
]}

OLEFSKY, JM ^{[1
]}

机构：

[1] VET ADM HOSP, DENVER, CO 80220 USA

来源：

JOURNAL OF CLINICAL INVESTIGATION | 1980年 / 65卷 / 06期

关键词：

D O I：

10.1172/JCI109790

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：1272 / 1284

页数：13

共 45 条

[1] DEFECT IN INSULIN BINDING TO RECEPTORS IN OBESE MAN - AMELIORATION WITH CALORIE RESTRICTION
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[2] FLUCTUATIONS IN AFFINITY AND CONCENTRATION OF INSULIN RECEPTORS ON CIRCULATING MONOCYTES OF OBESE PATIENTS - EFFECTS OF STARVATION, REFEEDING, AND DIETING
BAR, RS
GORDEN, P
ROTH, J
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DEMEYTS, P
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1976, 58 (05) : 1123 - 1135
[3] BJORNTORP P, 1971, EUR J CLIN INVEST, V1, P480, DOI 10.1111/j.1365-2362.1971.tb00559.x
[4] EFFECTS OF FEEDING STATES ON LIPID RADIOACTIVITY IN LIVER, MUSCLE AND ADIPOSE TISSUE AFTER INJECTION OF LABELLED GLUCOSE IN RAT
BJORNTORP, P
KROTKIEWSKI, M
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[J]. ACTA PHYSIOLOGICA SCANDINAVICA, 1970, 80 (01): : 29 - +
[5] BJURULF P, 1959, Acta Med Scand Suppl, V349, P1
[6] PORTAL AND PERIPHERAL VEIN IMMUNOREACTIVE INSULIN CONCENTRATIONS BEFORE AND AFTER GLUCOSE INFUSION
BLACKARD, WG
NELSON, NC
[J]. DIABETES, 1970, 19 (05) : 302 - &
[7] EFFECT OF GLUCAGON ON GLUCOSE PRODUCTION DURING INSULIN DEFICIENCY IN DOG
CHERRINGTON, AD
LACY, WW
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[J]. JOURNAL OF CLINICAL INVESTIGATION, 1978, 62 (03) : 664 - 677
[8] CHIASSON JL, 1977, FED PROC, V36, P229
[9] CELLULAR BASIS OF INSULIN INSENSITIVITY IN LARGE RAT ADIPOCYTES
CZECH, MP
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1976, 57 (06) : 1523 - 1532
[10] INSULIN BINDING TO MONOCYTES AND INSULIN ACTION IN HUMAN OBESITY, STARVATION, AND REFEEDING
DEFRONZO, RA
SOMAN, V
SHERWIN, RS
HENDLER, R
FELIG, P
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1978, 62 (01) : 204 - 213

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