MOLECULAR DISSECTION OF THE SECRETORY PATHWAY

被引：936

作者：

ROTHMAN, JE ^{[1
]}

ORCI, L ^{[1
]}

机构：

[1] UNIV GENEVA, INST HISTOL & EMBRYOL, DEPT MORPHOL, CH-1211 GENEVA 4, SWITZERLAND

来源：

NATURE | 1992年 / 355卷 / 6359期

关键词：

D O I：

10.1038/355409a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A combination of biochemistry in animal cell-free systems and genetics in yeast is revealing the molecular machinery of the secretory pathway of eukaryotes. Transporting vesicles have a simple coat structure and employ a general mechanism for fusion that is conserved in evolution. © 1992 Nature Publishing Group.

引用

页码：409 / 415

页数：7

共 110 条

[1] STRUCTURAL RELATIONSHIPS BETWEEN CLATHRIN ASSEMBLY PROTEINS FROM THE GOLGI AND THE PLASMA-MEMBRANE
AHLE, S
MANN, A
EICHELSBACHER, U
UNGEWICKELL, E
[J]. EMBO JOURNAL, 1988, 7 (04) : 919 - 929
[2] Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts
ANDERSON, RGW
BROWN, MS
GOLDSTEIN, JL
[J]. CELL, 1977, 10 (03) : 351 - 364
[3] RECONSTITUTION OF SEC GENE PRODUCT-DEPENDENT INTERCOMPARTMENTAL PROTEIN-TRANSPORT
BAKER, D
HICKE, L
REXACH, M
SCHLEYER, M
SCHEKMAN, R
[J]. CELL, 1988, 54 (03) : 335 - 344
[4] SMALL GTP-BINDING PROTEINS IN VESICULAR TRANSPORT
BALCH, WE
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 1990, 15 (12) : 473 - 477
[5] RECONSTITUTION OF THE TRANSPORT OF PROTEIN BETWEEN SUCCESSIVE COMPARTMENTS OF THE GOLGI MEASURED BY THE COUPLED INCORPORATION OF N-ACETYLGLUCOSAMINE
BALCH, WE
DUNPHY, WG
BRAELL, WA
ROTHMAN, JE
[J]. CELL, 1984, 39 (02) : 405 - 416
[6] SEQUENTIAL INTERMEDIATES IN THE PATHWAY OF INTERCOMPARTMENTAL TRANSPORT IN A CELL-FREE SYSTEM
BALCH, WE
GLICK, BS
ROTHMAN, JE
[J]. CELL, 1984, 39 (03) : 525 - 536
[7] BALCH WE, 1989, J BIOL CHEM, V264, P16965
[8] VESICULAR TRANSPORT BETWEEN THE ENDOPLASMIC-RETICULUM AND THE GOLGI STACK REQUIRES THE NEM-SENSITIVE FUSION PROTEIN
BECKERS, CJM
BLOCK, MR
GLICK, BS
ROTHMAN, JE
BALCH, WE
[J]. NATURE, 1989, 339 (6223) : 397 - 398
[9] SEMI-INTACT CELLS PERMEABLE TO MACROMOLECULES - USE IN RECONSTITUTION OF PROTEIN-TRANSPORT FROM THE ENDOPLASMIC-RETICULUM TO THE GOLGI-COMPLEX
BECKERS, CJM
KELLER, DS
BALCH, WE
[J]. CELL, 1987, 50 (04) : 523 - 534
[10] BENTZ J, 1991, DRUG ANESTHETIC EFFE, P259

← 1 2 3 4 5 6 7 8 9 10 →