TOXIC EFFECT ON HUMAN SPERMATOZOA BY CHLAMYDIA-TRACHOMATIS PURIFIED LIPOPOLYSACCHARIDE

被引：10

作者：

GALDIERO, F

SOMMESE, L

GORGA, F

GALDIERO, E

RIZZO, A

AJELLO, M

机构：

[1] UNIV ROMA,FAC FARM,IST MICROBIOL,ROME,ITALY

[2] CNR,AREA RIC,NAPLES,ITALY

来源：

FEMS MICROBIOLOGY LETTERS | 1994年 / 115卷 / 2-3期

关键词：

CHLAMYDIA TRACHOMATIS; LIPOPOLYSACCHARIDE; SPERMATOZOA;

D O I：

10.1111/j.1574-6968.1994.tb06637.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We have investigated the effect that lipopolysaccharide extracted from Chlamydia trachomatis has on human spermatozoa. A lipopolysaccharide of 0.1 mu g ml(-1) caused a spermatozoa mortality rate of 65+/-4% evaluated by eosin exclusion test. The toxic activity occurred rapidly even after brief incubation times, reaching the maximum (100% mortality) within 60 min.

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页码：197 / 200

页数：4

相关论文

共 16 条

[1] SPERMICIDAL ACTIVITY OF BACTERIAL ENDOTOXIN [J].

DENNIS, SM .

NATURE, 1962, 195 (4847) :1227-&

[2] THE ACTION OF LPS PORINS AND PEPTIDOGLYCAN FRAGMENTS ON HUMAN-SPERMATOZOA [J].

GALDIERO, F ;

GORGA, F ;

BENTIVOGLIO, C ;

MANCUSO, R ;

GALDIERO, E ;

TUFANO, MA .

INFECTION, 1988, 16 (06) :349-353

[3] INFLAMMATORY EFFECTS OF SALMONELLA-TYPHIMURIUM PORINS [J].

GALDIERO, F ;

TUFANO, MA ;

GALDIERO, M ;

MASIELLO, S ;

DIROSA, M .

INFECTION AND IMMUNITY, 1990, 58 (10) :3183-3186

[4]

GORDON FB, 1965, P SOC EXP BIOL MED, V118, P354, DOI 10.3181/00379727-118-29841

[5]

ISSELBACHER KJ, 1980, PRINCIPLES INTERNAL, P231

[6] CLEAVAGE OF STRUCTURAL PROTEINS DURING ASSEMBLY OF HEAD OF BACTERIOPHAGE-T4 [J].

LAEMMLI, UK .

NATURE, 1970, 227 (5259) :680-+

[7]

LANE RC, 1948, STERILITY IMPAIRED F, P78

[8] CHEMICAL CHARACTERIZATION OF CHLAMYDIA-TRACHOMATIS LIPOPOLYSACCHARIDE [J].

NURMINEN, M ;

RIETSCHEL, ET ;

BRADE, H .

INFECTION AND IMMUNITY, 1985, 48 (02) :573-575

[9] IMMUNOLOGICALLY RELATED KETODEOXYOCTONATE-CONTAINING STRUCTURES IN CHLAMYDIA-TRACHOMATIS, RE MUTANTS OF SALMONELLA SPECIES, AND ACINNETOBACTER-CALCOACETICUS VAR ANITRATUS [J].

NURMINEN, M ;

WAHLSTROM, E ;

KLEEMOLA, M ;

LEINONEN, M ;

SAIKKU, P ;

MAKELA, PH .

INFECTION AND IMMUNITY, 1984, 44 (03) :609-613

[10] STUDIES ON GRAM-NEGATIVE CELL WALL .1. EVIDENCE FOR ROLE OF 2-KETO-3DEOXYOCTONATE IN LIPOPOLYSACCHARIDE OF SALMONELLA TYPHIMURIUM [J].

OSBORN, MJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1963, 50 (03) :499-&