Curacins B and C, new antimitotic natural products from the marine cyanobacterium Lyngbya majuscula

被引：49

作者：

Yoo, HD ^{[1
]}

Gerwick, WH ^{[1
]}

机构：

[1] OREGON STATE UNIV,COLL PHARM,CORVALLIS,OR 97331

来源：

JOURNAL OF NATURAL PRODUCTS | 1995年 / 58卷 / 12期

关键词：

D O I：

10.1021/np50126a029

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new and potent antimitotic metabolites, curacins B [2] and C [3], were isolated from a Curacao collect ion of Lyngbya majuscula. The structures of 2 and 3, geometrical isomers of the known compound curacin A [1], were determined by derailed spectroscopic analysis in comparison with 1. The absolute stereochemical configuration of 2 was deduced ro be 2R,13R,19R,21S by ics thermally induced interconversion with 1.

引用

页码：1961 / 1965

页数：5

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