ACTIVITY OF SOME PROTEOLYTIC-ENZYMES IN NORMAL AND DYSTROPHIC HUMAN-MUSCLE

被引：20

作者：

KAR, NC ^{[1
]}

PEARSON, CM ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT MED,LOS ANGELES,CA 90024

来源：

CLINICAL BIOCHEMISTRY | 1979年 / 12卷 / 02期

关键词：

D O I：

10.1016/S0009-9120(79)80001-6

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

1.The following proteolytic enzymes were measured in muscles of control subjects and patients with muscular dystrophies and related neuromuscular diseases: an elastase-like enzyme, carboxypeptidase A, carboxypeptidase B and pyroglutamyl peptidase.2.Elastase-like enzyme and carboxypeptidase B did not show significant alterations in various disease conditions that were examined.3.Carboxypeptidase A was moderately elevated in dystrophic as well as other diseased muscles.4.Pyroglutamyl peptidase was not markedly altered in any disease condition except that is was slightly lower in dystrophic muscles. © 1979 Canadian Society of Clinical Chemists.

引用

页码：37 / 39

页数：3

共 34 条

[1]

BURGUS R, 1969, CR ACAD SCI D NAT, V269, P1870

[2] PYRROLIDONYL PEPTIDASE . AN ENZYME FOR SELECTIVE REMOVAL OF PYRROLIDONECARBOXYLIC ACID RESIDUES FROM POLYPEPTIDES [J].

DOOLITTLE, RF ;

ARMENTROUT, RW .

BIOCHEMISTRY, 1968, 7 (02) :516-+

[3]

FOLK JE, 1958, J BIOL CHEM, V231, P379

[4]

GOLDBERG AL, 1977, PATHOGENESIS HUMAN M, P376

[5]

GORDON S, 1977, FED P, V36, P2070

[6]

JANOFF A, 1973, LAB INVEST, V29, P458

[7]

JANOFF A, 1971, P SOC EXP BIOL MED, V136, P1045

[8] ACETYL-DL-PHENYLALANINE BETA-NAPHTHYL ESTERASE-ACTIVITY IN HUMAN MUSCLE DISEASE [J].

KAR, NC ;

PEARSON, CM .

BIOCHEMICAL MEDICINE, 1978, 20 (01) :63-69

[9] DIPEPTIDYL PEPTIDASES IN HUMAN MUSCLE DISEASE [J].

KAR, NC ;

PEARSON, CM .

CLINICA CHIMICA ACTA, 1978, 82 (1-2) :185-192

[10] ACID, NEUTRAL AND ALKALINE CATHEPSINS IN NORMAL AND DISEASED HUMAN MUSCLE [J].

KAR, NC ;

PEARSON, CM .

ENZYME, 1972, 13 (04) :188-196

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