THE CARDIOVASCULAR EFFECTS OF BETA-ADRENERGIC AGONIST DRUGS ADMINISTERED BY NEBULIZATION

被引:21
作者
FLATT, A
CRANE, J
PURDIE, G
KWONG, T
BEASLEY, R
BURGESS, C
机构
[1] WELLINGTON SCH MED,DEPT MED,WELLINGTON,NEW ZEALAND
[2] WELLINGTON SCH MED,DEPT COMMUNITY HLTH,WELLINGTON,NEW ZEALAND
关键词
D O I
10.1136/pgmj.66.772.98
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The cardiovascular effects of equal doses (5 mg) of nebulised fenoterol, salbutamol and terbutaline were compared in 12 healthy individuals in a double-blind, placebo-controlled study. Measurements of heart rate, blood pressure, systolic time intervals, QTc interval and T-wave amplitude were made at baseline and at 15, 30, 45, 60 and 90 minutes after nebulisation. Fenoterol caused significantly greater chronotropic electrocardiographic and inotropic effects than either salbutamol or terbutaline. The peak effects after terbutaline occurred later than those after fenoterol or salbutamol.
引用
收藏
页码:98 / 101
页数:4
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