EFFECT OF CORTICOSTEROID AND IRRADIATION ON CECAL AMEBIC INFECTION IN RATS

被引：19

作者：

VINAYAK, VK ^{[1
]}

CHITKARA, NL ^{[1
]}

CHHUTTANI, PN ^{[1
]}

机构：

[1] POSTGRAD INST MED EDUC & RES,DEPT EXPTL MED,CHANDIGARH,INDIA

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1979年 / 73卷 / 03期

关键词：

D O I：

10.1016/0035-9203(79)90080-4

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Albino rats (Wistar strain) were pretreated with corticosteroid, irradiation or both to study the effect on the outcome of amoebic infection given intracaecally. The number of animals with lesions amongst “treated” groups was not significantly different from that amongst untreated control animals (P>0.05) but amoebic pathology was markedly exacerbated amongst the treated animals. It is thus thought that once the amoebic infection is established. amoebae become better established for penetration in the immuno-depressed host. The study further suggests that corticosteroid therapy could aggravate an otherwise sub-clinical amoebic infection in man. © 1979 Oxford University Press.

引用

页码：266 / 268

页数：3

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