AMINO-ACID-SEQUENCE ANALYSIS OF A MOUSE INTERLEUKIN-5 RECEPTOR PROTEIN REVEALS HOMOLOGY WITH A MOUSE INTERLEUKIN-3 RECEPTOR PROTEIN

被引：9

作者：

DEVOS, R

VANDEKERCKHOVE, J

ROLINK, A

PLAETINCK, G

VANDERHEYDEN, J

FIERS, W

TAVERNIER, J

机构：

[1] STATE UNIV GHENT,GENET LAB,B-9000 GHENT,BELGIUM

[2] STATE UNIV GHENT,MOLEC BIOL LAB,B-9000 GHENT,BELGIUM

[3] BASEL INST IMMUNOL,CH-4005 BASEL,SWITZERLAND

来源：

EUROPEAN JOURNAL OF IMMUNOLOGY | 1991年 / 21卷 / 05期

关键词：

D O I：

10.1002/eji.1830210533

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A polypeptide chain for the mouse interleukin 5 receptor (IL5R) was purified from detergent-lysed B13 cells, a mouse IL5-dependent pre-B cell line. Purification was by a single immunoaffinity chromatographic step using an anti-mouse IL5R monoclonal antibody, R52. Internal amino acid sequence was obtained from four trypsin-generated peptides. All peptides were found to be present in the published amino acid sequence of a mouse IL3R and the mouse IL3R-like protein deduced from the cDNA. This indicates that the mouse IL5R and the mouse IL3R have a homologous polypeptide in common and suggests that the specificity of these lymphokine receptors is mainly generated by association with another ligand-specific polypeptide chain.

引用

页码：1315 / 1317

页数：3

共 14 条

[1] BIOTINYLATION - AN ALTERNATIVE TO RADIOIODINATION FOR THE IDENTIFICATION OF CELL-SURFACE ANTIGENS IN IMMUNOPRECIPITATES
COLE, SR
ASHMAN, LK
EY, PL
[J]. MOLECULAR IMMUNOLOGY, 1987, 24 (07) : 699 - 705
[2] CLONING AND EXPRESSION OF A GENE ENCODING AN INTERLEUKIN-3 RECEPTOR-LIKE PROTEIN - IDENTIFICATION OF ANOTHER MEMBER OF THE CYTOKINE RECEPTOR GENE FAMILY
GORMAN, DM
ITOH, N
KITAMURA, T
SCHREURS, J
YONEHARA, S
YAHARA, I
ARAI, KI
MIYAJIMA, A
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (14) : 5459 - 5463
[3] HITOSHI Y, 1990, J IMMUNOL, V144, P4218
[4] CLONING OF AN INTERLEUKIN-3 RECEPTOR GENE - A MEMBER OF A DISTINCT RECEPTOR GENE FAMILY
ITOH, N
YONEHARA, S
SCHREURS, J
GORMAN, DM
MARUYAMA, K
ISHII, A
YAHARA, I
ARAI, K
MIYAJIMA, A
[J]. SCIENCE, 1990, 247 (4940) : 324 - 327
[5] RECEPTORS FOR T-CELL-REPLACING FACTOR INTERLEUKIN-5 - SPECIFICITY, QUANTITATION, AND ITS IMPLICATION
MITA, S
HARADA, N
NAOMI, S
HITOSHI, Y
SAKAMOTO, K
AKAGI, M
TOMINAGA, A
TAKATSU, K
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1988, 168 (03) : 863 - 878
[6] CHARACTERIZATION OF HIGH-AFFINITY RECEPTORS FOR INTERLEUKIN-5 ON INTERLEUKIN-5-DEPENDENT CELL-LINES
MITA, S
TOMINAGA, A
HITOSHI, Y
SAKAMOTO, K
HONJO, T
AKAGI, M
KIKUCHI, Y
YAMAGUCHI, N
TAKATSU, K
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (07) : 2311 - 2315
[7] CHARACTERIZATION OF INTERLEUKIN-5 RECEPTORS ON EOSINOPHILIC SUBLINES FROM HUMAN PROMYELOCYTIC LEUKEMIA (HL-60) CELLS
PLAETINCK, G
VANDERHEYDEN, J
TAVERNIER, J
FACHE, I
TUYPENS, T
FISCHKOFF, S
FIERS, W
DEVOS, R
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1990, 172 (03) : 683 - 691
[8] MONOCLONAL-ANTIBODIES REACTIVE WITH THE MOUSE INTERLEUKIN-5 RECEPTOR
ROLINK, AG
MELCHERS, F
PALACIOS, R
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1989, 169 (05) : 1693 - 1701
[9] THE BIOLOGICAL ROLE OF INTERLEUKIN-5
SANDERSON, CJ
[J]. INTERNATIONAL JOURNAL OF CELL CLONING, 1990, 8 : 147 - 154
[10] SCHNEIDER C, 1982, J BIOL CHEM, V257

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