ASYMMETRIC ALLYLBORATIONS OF 3-DECYNAL DICOBALT HEXACARBONYL - COBALT INDUCED REVERSAL OF ENANTIOSELECTIVITY AND APPLICATIONS TO HIGHLY DIASTEREOSELECTIVE INTRAMOLECULAR PAUSON-KHAND REACTIONS

被引：35

作者：

ROUSH, WR

PARK, JC

机构：

[1] Department of Chemistry, Indiana University, Bloomington

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 44期

关键词：

D O I：

10.1016/0040-4039(91)80148-Y

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The enantioselective crotylborations of 3-decynal dicobalt hexacarbonyl (10) provide a very convenient route to stereochemically defined 1,6-enyne dicobalt hexacarbonyl complexes (12, 13) that undergo highly diastereoselective intramolecular Pauson-Khand cyclizations to bicyclooctenones 14 and 15 (90% e.e. for 15). The mechanistically significant reversal of enantioselectivity in the allylborations of 10 compared to the parent 3-decynal 5 is also reported.

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页码：6285 / 6288

页数：4

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