DNA-BINDING STUDIES WITH 6BT AND 5I - IMPLICATIONS FOR DNA-BINDING CARCINOGENICITY AND DNA-BINDING MUTAGENICITY CORRELATIONS

被引：6

作者：

DASHWOOD, RH

COMBES, RD

ASHBY, J

机构：

[1] PORTSMOUTH POLYTECH,SCH BIOL SCI,PORTSMOUTH P01 2DY,HANTS,ENGLAND

[2] ICI PLC,CENT TOXICOL LAB,MACCLESFIELD SK10 4TG,CHESHIRE,ENGLAND

来源：

MUTATION RESEARCH | 1988年 / 198卷 / 01期

关键词：

D O I：

10.1016/0027-5107(88)90040-1

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：61 / 68

页数：8

共 18 条

[1] THE POSSIBLE ROLE OF AZOREDUCTION IN THE BACTERIAL MUTAGENICITY OF 4-DIMETHYLAMINOAZOBENZENE (DAB) AND 2 OF ITS ANALOGS (6BT AND 5I) [J].

ASHBY, J ;

LEFEVRE, PA ;

CALLANDER, RD .

MUTATION RESEARCH, 1983, 116 (3-4) :271-279

[2] AN ASSESSMENT OF THE INVIVO RAT HEPATOCYTE DNA-REPAIR ASSAY [J].

ASHBY, J ;

LEFEVRE, PA ;

BURLINSON, B ;

PENMAN, MG .

MUTATION RESEARCH, 1985, 156 (1-2) :1-18

[3] LIMITATIONS OF METABOLIC-ACTIVATION SYSTEMS USED WITH INVITRO TESTS FOR CARCINOGENS [J].

BIGGER, CAH ;

TOMASZEWSKI, JE ;

DIPPLE, A ;

LAKE, RS .

SCIENCE, 1980, 209 (4455) :503-505

[4] CARCINOGENIC ACTIVITY OF ANALOGS OF P-DIMETHYLAMINOAZOBENZENE .6. ACTIVITY OF BENZIMIDAZOLE AND BENZTHIAZOLE ANALOGS [J].

BROWN, EV ;

SANCHORAWALA, CJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (05) :1074-+

[5] CARCINOGENIC ACTIVITY OF ANALOGS OF P-DIMETHYLAMINOAZOBENZENE .9. ACTIVITY OF QUINOXALINE AND INDAZOLE ANALOGS [J].

BROWN, EV ;

FISHER, WM .

JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (06) :1113-&

[6] A REVIEW OF THE GENOTOXICITY OF FOOD, DRUG AND COSMETIC COLORS AND OTHER AZO, TRIPHENYLMETHANE AND XANTHENE DYES [J].

COMBES, RD ;

HAVELANDSMITH, RB .

MUTATION RESEARCH, 1982, 98 (02) :101-243

[7] MUTAGENICITY TO SALMONELLA OF 4 DERIVATIVES OF THE AZO MUTAGEN 5I - SOME IMPLICATIONS FOR STRUCTURE ACTIVITY DATABASES AND THE EVALUATION OF COMBINATIONS OF MUTAGENS [J].

DASHWOOD, RH ;

COMBES, RD ;

PATON, D ;

ASHBY, J .

MUTAGENESIS, 1986, 1 (04) :261-265

[8] THE USE OF INVIVO-LIKE CONCENTRATIONS OF CHEMICALS FOR VALIDATION OF INVITRO SHORT-TERM GENOTOXICITY ASSAYS - AN INVIVO EQUIVALENT DOSE CONCEPT [J].

DASHWOOD, RH ;

COMBES, RD .

MUTAGENESIS, 1987, 2 (04) :249-251

[9] THE DISPOSITION AND INVIVO COVALENT BINDING TO LIVER DNA OF THE MONOAZODYES 6-(PARA-DIMETHYLAMINOPHENYLAZO)BENZOTHIAZOLE (6BT) AND 5-(PARA-DIMETHYLAMINOPHENYLAZO)INDAZOLE (5I) AFTER ADMINISTRATION TO THE RAT [J].

DASHWOOD, RH ;

COMBES, RD ;

ASHBY, J .

CARCINOGENESIS, 1986, 7 (06) :1029-1033

[10] DEFICIENCIES IN THE COVALENT BINDING INDEX (CBI) FOR EXPRESSING INVIVO BINDING TO DNA WITH RESPECT TO PREDICTING CHEMICAL CARCINOGENICITY - A PROPOSAL FOR A TARGET-ORGAN BINDING INDEX [J].

DASHWOOD, RH ;

COMBES, RD .

MUTATION RESEARCH, 1987, 190 (03) :173-175

← 1 2 →