RADIATION-THERAPY FOR SKIN-CANCER NEAR THE EYE - KILOVOLTAGE X-RAYS VERSUS ELECTRONS

被引:46
作者
AMDUR, RJ [1 ]
KALBAUGH, KJ [1 ]
EWALD, LM [1 ]
PARSONS, JT [1 ]
MENDENHALL, WM [1 ]
BOVA, FJ [1 ]
MILLION, RR [1 ]
机构
[1] UNIV FLORIDA,HLTH SCI CTR,DEPT RADIAT ONCOL,POB 100385,GAINESVILLE,FL 32610
来源
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 1992年 / 23卷 / 04期
关键词
SKIN NEOPLASMS; X-RAY THERAPY; ELECTRONS; RADIOTHERAPY; RADIATION DOSAGE; EYE;
D O I
10.1016/0360-3016(92)90650-7
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
When skin cancer near the eye is irradiated, a corneal shield is placed between the lids and globe to protect ocular structures. The effectiveness of the shield was evaluated with 250 kVp x-ray and 6-20 MeV electron beams. To simulate the clinical situation, a face phantom was constructed out of solid pieces of water-equivalent epoxy. In the region of the eye the phantom was milled to the exact contour of a human face. The phantom was used to reconstruct the setup that had been used to treat a patient with a 1-cm basal cell carcinoma of the mid portion of the lower lid. A medium-sized corneal shield (2-mm-thick lead plated with 0.1 mm gold) was placed on the eye portion of the phantom. A contoured lead (6 mm thick) face mask was placed on the surface of the phantom to define a 3-cm diameter radiation field that included only the inferior hemisphere of the shield. The doses that the cornea, lens, and retina would receive beneath the midpoint of the inferior hemisphere of the shield were measured using thermoluminescent and film dosimetry. With 6 to 8 MeV electrons, the corneal dose was 2 to 4 times higher than with 250 kVp x-rays. Corneal and lens doses rose rapidly with increasing electron beam energy such that with > 8 MeV the shield would provide relatively poor ocular protection. A scanning ion chamber and film dosimetry were used to determine the isodose profiles of 250 kVp x-ray and 6 MeV electron beams for a 3-cm diameter field collimated on the surface. With 250 kVp x-rays the 95% isodose area was 32% wider than with 6 MeV electrons. The ease of shielding and the ability to minimize field size argue in favor of kilovoltage x-rays for early-stage skin cancer near the eye.
引用
收藏
页码:769 / 779
页数:11
相关论文
共 31 条
[1]
CARCINOMA OF EYELID [J].
BERTELSEN, K ;
GADEBERG, C .
ACTA RADIOLOGICA-THERAPY PHYSICS BIOLOGY, 1978, 17 (01) :58-64
[2]
Bova F J, 1990, Med Dosim, V15, P83
[3]
COBB GM, 1964, CAN MED ASSOC J, V91, P743
[4]
FAYOS JV, 1962, ARCH OPHTHALMOL-CHIC, V67, P298
[5]
TUMORS OF EYELIDS AND THEIR TREATMENT BY RADIOTHERAPY [J].
FITZPATR.PJ ;
THOMPSON, GA ;
ALLT, WEC ;
JAMIESON, DM .
RADIOLOGY, 1972, 104 (03) :661-&
[6]
BASAL AND SQUAMOUS-CELL CARCINOMA OF THE EYELIDS AND THEIR TREATMENT BY RADIOTHERAPY [J].
FITZPATRICK, PJ ;
THOMPSON, GA ;
EASTERBROOK, WM ;
GALLIE, BL ;
PAYNE, DG .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1984, 10 (04) :449-454
[7]
DOSE ENHANCEMENT FROM BACKSCATTERED RADIATION AT TISSUE-METAL INTERFACES IRRADIATED WITH HIGH-ENERGY ELECTRONS [J].
GAGNON, WF ;
CUNDIFF, JH .
BRITISH JOURNAL OF RADIOLOGY, 1980, 53 (629) :466-470
[8]
CHECK OF ELECTRON BACKSCATTERING COEFFICIENTS AT 10 AND 20 MEV [J].
HARDER, D ;
METZGER, L .
ZEITSCHRIFT FUR NATURFORSCHUNG PART A-ASTROPHYSIK PHYSIK UND PHYSIKALISCHE CHEMIE, 1968, A 23 (10) :1675-&
[9]
JANSON PP, 1990, 9TH ANN M ESTRO
[10]
JOHNS HE, 1983, PHYSICS RADIOLOGY, P283