INHIBITION OF ACETYL-COENZYME A CARBOXYLASE BY THE NOVEL GRASS-SELECTIVE HERBICIDE 3-(2,4-DICHLOROPHENYL)-PERHYDROINDOLIZINE-2,4-DIONE

被引:17
作者
BABCZINSKI, P [1 ]
FISCHER, R [1 ]
机构
[1] BAYER AG,PFLANZENSCHUTZZENTRUM MONHEIM,CHEM RES,W-5090 LEVERKUSEN,GERMANY
来源
PESTICIDE SCIENCE | 1991年 / 33卷 / 04期
关键词
D O I
10.1002/ps.2780330408
中图分类号
S3 [农学(农艺学)];
学科分类号
0901 ;
摘要
The novel herbicidal compound 3-(2,4-dichlorophenyl)-perhydroindolizine-2,4-dione which is active as a pre- and post-emergence grass-selective herbicide is a new type of inhibitor of plant acetyl-coenzyme A carboxylase (ACCase; E. C. 6.4.1.2). This has been demonstrated by in-vitro experiments using isolated corn enzyme. Besides an I50 value of 4.7-mu-M under the assay conditions used, a mixed-type inhibitory activity on the enzyme is established. The compound is inactive on rat liver ACCase enzyme and shows decreased activity (pI50 less than 3.0) on the spinach enzyme.
引用
收藏
页码:455 / 466
页数:12
相关论文
共 18 条