ALTERED CELL FATE IN LICL-TREATED SEA-URCHIN EMBRYOS

被引：43

作者：

NOCENTEMCGRATH, C ^{[1
]}

MCISAAC, R ^{[1
]}

ERNST, SG ^{[1
]}

机构：

[1] TUFTS UNIV,DEPT BIOL,MEDFORD,MA 02155

来源：

DEVELOPMENTAL BIOLOGY | 1991年 / 147卷 / 02期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0012-1606(91)90302-J

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Endo16 is a lineage-specific protein expressed during embryogenesis in the sea urchin, Strongylocentrotus purpuratus. We have examined the effects of various concentrations of lithium chloride, a well-known vegetalizing agent, on Endo16 expression in whole sea urchin embryos. Our results show that treatment with LiCl causes increased steady-state levels of Endo16 transcripts. An increase in the number of endodermal cells in treated embryos demonstrates a change in cell lineage. In addition, we observed a delay in development of lithium-treated embryos that is accompanied by a delay in the expression of a late class histone H2B gene. © 1991.

引用

页码：445 / 450

页数：6

共 20 条

[1] SIMULTANEOUS EXPRESSION OF EARLY AND LATE HISTONE MESSENGER-RNAS IN INDIVIDUAL CELLS DURING DEVELOPMENT OF THE SEA-URCHIN EMBRYO [J].