APPLICATION OF OPTIMAL-DESIGN METHODOLOGY TO THE PHASE-TRANSFER CATALYTIC BENZYLATION OF MALONONITRILE

被引：5

作者：

ELGUERO, J

GOYA, P

PAEZ, JA

DIEZBARRA, E

DELAHOZ, A

MORENO, A

MATHIEU, D

LUU, RPT

SERGENT, M

机构：

[1] CSIC,INST QUIM MED,E-28006 MADRID,SPAIN

[2] UNIV CASTILLA LA MANCHA,FAC CIENCIAS QUIM,E-13071 CIUDAD REAL,SPAIN

[3] UNIV AIX MARSEILLE 2,FAC SCI,F-13397 MARSEILLE 13,FRANCE

[4] IUT,LPRAI,F-13397 MARSEILLE 13,FRANCE

来源：

CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS | 1990年 / 9卷 / 03期

关键词：

D O I：

10.1016/0169-7439(90)80079-L

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

Experimental design methodology using NEMROD software programs has been applied to achieve selective monobenzylation of malononitrile under PTC conditions. Different mathematical models have been used to study the variation in selectivity and yield of the reaction with different qualitative and quantitative experimental variables.

引用

页码：287 / 292

页数：6