学术探索
学术期刊
新闻热点
数据分析
智能评审

CURRENT ISSUES IN THE USE OF THEOPHYLLINE

被引：37
作者：
MILGROM, H
BENDER, B
机构：
来源：
AMERICAN REVIEW OF RESPIRATORY DISEASE | 1993年 / 147卷 / 06期
关键词：
D O I：
10.1164/ajrccm/147.6_Pt_2.S33
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Theophylline is a safe and effective medication for the management of chronic asthma. It reduces nocturnal bronchospasm and airways hyperresponsiveness, and its addition to effective doses of beta-agonists and corticosteroids leads to further improvement in symptom control. These properties are the result of actions other than simple bronchodilation, and there is a strong possibility that anti-inflammatory activity accounts for its clinical advantages. Serious side effects are uncommon and their rate can be further reduced through appropriate precautions. Recent studies have alleviated the concern over cognitive and behavioral side effects in children.
引用
收藏
页码：S33 / S39
页数：7
相关论文
共 86 条
[1]   INCREASE IN PLASMA-FREE FATTY-ACIDS AND NATRIURESIS BY XANTHINES MAY REFLECT ADENOSINE ANTAGONISM [J].
ANDERSSON, KE ;
JOHANNESSON, N ;
KARLBERG, B ;
PERSSON, CGA .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 26 (01) :33-38
[2]  
ARKINSTALL WW, 1987, AM REV RESPIR DIS, V135, P316
[3]  
BARNES PJ, 1982, LANCET, V1, P299
[4]   INFLAMMATORY MECHANISMS AND NOCTURNAL ASTHMA [J].
BARNES, PJ .
AMERICAN JOURNAL OF MEDICINE, 1988, 85 (1B) :64-70
[5]  
BENDER B, 1992, JAMA-J AM MED ASSOC, V267, P2621
[6]   PSYCHOLOGICAL CHANGE ASSOCIATED WITH THEOPHYLLINE TREATMENT OF ASTHMATIC-CHILDREN - A 6-MONTH STUDY [J].
BENDER, BG ;
LERNER, JA ;
IKLE, D ;
COMER, C ;
SZEFLER, S .
PEDIATRIC PULMONOLOGY, 1991, 11 (03) :233-242
[7]   NEED FOR THEOPHYLLINE IN SEVERE STEROID-REQUIRING ASTHMATICS [J].
BRENNER, M ;
BERKOWITZ, R ;
MARSHALL, N ;
STRUNK, RC .
CLINICAL ALLERGY, 1988, 18 (02) :143-150
[8]   THEOPHYLLINE PARTIALLY INHIBITS BRONCHOCONSTRICTION CAUSED BY INHALED HISTAMINE IN SUBJECTS WITH ASTHMA [J].
CARTIER, A ;
LEMIRE, I ;
LARCHEVEQUE, J ;
GHEZZO, H ;
MARTIN, RR ;
MALO, JL .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1986, 77 (04) :570-575
[9]   CD4 LYMPHOCYTE-T ACTIVATION IN ACUTE SEVERE ASTHMA - RELATIONSHIP TO DISEASE SEVERITY AND ATOPIC STATUS [J].
CORRIGAN, CJ ;
KAY, AB .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1990, 141 (04) :970-977
[10]  
CRESCIOLI S, 1991, ANN ALLERGY, V66, P245
123456789