EVALUATION OF 2 FORMULATIONS OF DIHYDROCODEINE USING PATIENT-CONTROLLED ANALGESIA

被引：6

作者：

AITKEN, HA

CLARK, EC

MCARDLE, CS

DIMITRI, W

KENNY, GNC

机构：

[1] UNIV GLASGOW,ROYAL INFIRM,DEPT ANAESTHESIA,8-16 ALEXANDRA PARADE,GLASGOW G31 2ER,SCOTLAND

[2] UNIV GLASGOW,ROYAL INFIRM,DEPT SURG,GLASGOW G31 2ER,SCOTLAND

[3] UNIV GLASGOW,ROYAL INFIRM,DEPT CARDIAC SURG,GLASGOW G31 2ER,SCOTLAND

来源：

ANAESTHESIA | 1990年 / 45卷 / 07期

关键词：

Analgesics; dihydrocodeine; Pain; postoperative;

D O I：

10.1111/j.1365-2044.1990.tb14825.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

A randomised, double‐blind study of 90 patients after cardiac bypass surgery was undertaken to assess the relative analgesic efficacies of normal‐ and controlled‐release oral dihydrocodeine. Patients received either placebo, normal‐release dihydrocodeine, or controlled‐release dihydrocodeine at regular intervals on the first to third days after operation. This was supplemented in all groups by intravenous morphine administered on demand by a patient‐controlled analgesia system. Morphine requirements in the control group were significantly greater during this 48‐hour period than in either of the active groups (p < 0.01), but there was no statistically significant difference between the two active preparations. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：535 / 537

页数：3

共 6 条

[1] THE INFLUENCE OF PATIENT CHARACTERISTICS ON THE REQUIREMENTS FOR POSTOPERATIVE ANALGESIA - A REASSESSMENT USING PATIENT-CONTROLLED ANALGESIA [J].