THE EFFECT OF OVINE PROLACTIN ON THE EPIDIDYMAL SIALIC-ACID CONCENTRATION IN MALE-RATS

被引：4

作者：

GAUTAM, R ^{[1
]}

PEREIRA, BMJ ^{[1
]}

机构：

[1] UNIV ROORKEE,DEPT BIOSCI & BIOTECHNOL,REPROD BIOL LAB,ROORKEE 247667,UTTAR PRADESH,INDIA

来源：

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY | 1992年 / 19卷 / 07期

关键词：

ALBINO RAT; EPIDIDYMIS; ORCHIECTOMY; OVINE PROLACTIN; SIALIC ACID;

D O I：

10.1111/j.1440-1681.1992.tb00495.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

1. Previous experiments have shown that the level of sialic acid in the epididymis is influenced by factors originating in the testis. 2. To exclude interference from these factors, both orchidectomized and duct-ligated rats were used to study the potential role of prolactin in the epididymis. 3. When ovine prolactin was injected in orchidectomized rats, a dose-related increase in the level of sialic acid was observed in the epididymis. 4. That this action of prolactin is independent of androgen was confirmed by studies using bromocryptine, which decreases circulating endogenous prolactin. 5. The physiological role(s) of epididymal sialic acid production in response to prolactin remain to be established.

引用

页码：495 / 501

页数：7

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