EFFECT OF PROTEOLYTIC-ENZYMES ON BINDING OF COBALAMIN TO R-PROTEIN AND INTRINSIC-FACTOR - INVITRO EVIDENCE THAT A FAILURE TO PARTIALLY DEGRADE R-PROTEIN IS RESPONSIBLE FOR COBALAMIN MALABSORPTION IN PANCREATIC INSUFFICIENCY

被引：168

作者：

ALLEN, RH

SEETHARAM, B

PODELL, E

ALPERS, DH

机构：

[1] WASHINGTON UNIV,DEPT INTERNAL MED,DIV HEMATOL ONCOL,ST LOUIS,MO 63110

[2] WASHINGTON UNIV,DEPT INTERNAL MED,DIV GASTROENTEROL,ST LOUIS,MO 63110

来源：

关键词：

D O I：

10.1172/JCI108924

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：47 / 54

页数：8

共 27 条

[1] Allen R H, 1975, Prog Hematol, V9, P57
[2] ALLEN RH, 1973, J BIOL CHEM, V248, P3670
[3] ALLEN RH, 1973, J BIOL CHEM, V248, P3660
[4] Anson ML, 1938, J GEN PHYSIOL, V22, P78
[5] LABELING OF PROTEINS TO HIGH SPECIFIC RADIOACTIVITIES BY CONJUGATION TO A I-125-CONTAINING ACYLATING AGENT - APPLICATION TO RADIOIMMUNOASSAY
BOLTON, AE
HUNTER, WM
[J]. BIOCHEMICAL JOURNAL, 1973, 133 (03) : 529 - 538
[6] BURGER RL, 1974, J BIOL CHEM, V249, P7220
[7] COTTER R, 1977, FED PROC, V36, P594
[8] MALABSORPTION OF CRYSTALLINE VITAMIN-B12 IN CYSTIC-FIBROSIS
DEREN, JJ
ARORA, B
TOSKES, PP
HANSELL, J
SIBINGA, MS
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1973, 288 (18) : 949 - 950
[9] GRASBECK R, 1976, PROG FOOD NUTR SCI, V2, P192
[10] GUYTON AC, 1976, TXB MED PHYSL, P870