INCLUSION OF L-GLUCOSE WITHIN SPECIFICITY LIMITS OF ACTIVE SUGAR TRANSPORT SYSTEM OF HAMSTER SMALL INTESTINE

被引:41
作者
CASPARY, WF
CRANE, RK
机构
[1] Department of Physiology, Rutgers Medical School, New Brunswick, NJ
基金
美国国家科学基金会;
关键词
D O I
10.1016/0005-2736(68)90124-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Incubation in vitro of segments and everted sacs of hamster small intestine have been used to study the mode of absorption of l-glucose. By all current criteria, l-glucose is a substrate of the intestinal transport system for d-glucose. We have examined accumulation against a concentration gradient, substrate inhibition, phlorizin sensitivity, Na+ dependence, energy dependence and counterflow. The estimated Km value for l-glucose is 65 mM. © 1968.
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页码:395 / &
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