EFFECT ON FERTILITY OF IMMUNIZING FEMALE SHEEP WITH RAM SPERM ACROSIN AND HYALURONIDASE

被引：40

作者：

MORTON, DB ^{[1
]}

MCANULTY, PA ^{[1
]}

机构：

[1] STRANGEWAYS RES LAB,CAMBRIDGE CB1 4RN,ENGLAND

来源：

JOURNAL OF REPRODUCTIVE IMMUNOLOGY | 1979年 / 1卷 / 01期

关键词：

D O I：

10.1016/0165-0378(79)90030-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Female sheep were injected with highly purified and partially purified preparations of ram sperm acrosin and hyaluronidase. The fertility and immune response of the sheep were monitored. Fertility was not significantly reduced in any single group, though a positive correlation was observed between high antibody titres against acrosin and reduced fertility. Studies on the direct action of sera from the ewes on ejaculated ram spermatozoa did not show any evidence of sperm agglutination or immobilization. Similar studies with denuded spermatozoa (detergent induced 'acrosome reaction') sometimes resulted in agglutination and enzyme inhibition was also seen; there was no correlation between any of these parameters and pregnancy. © 1979.

引用

页码：61 / 73

页数：13

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