ENZYME-CATALYZED PEPTIDE-SYNTHESIS IN ICE

被引:68
作者
SCHUSTER, M
AAVIKSAAR, A
JAKUBKE, HD
机构
[1] KARL MARX UNIV,DEPT BIOCHEM,DIV BIOSCI,TALSTR 33,O-7010 LEIPZIG,GERMANY
[2] ESTONIAN ACAD SCI,INST CHEM PHYS & BIOPHYS,BIOORGAN CHEM LAB,TALLINN 200026,ESTONIA
关键词
D O I
10.1016/S0040-4020(01)81466-6
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new method for increasing product yield in kinetically controlled enzymatic peptide synthesis catalyzed by serine and cysteine proteases is proposed - freezing the reaction mixture. The use of the method in preparative synthesis has been demonstrated. © 1990.
引用
收藏
页码:8093 / 8102
页数:10
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