PHOTODYNAMIC THERAPY FOR CANCERS - A CLINICAL-TRIAL OF PORFIMER SODIUM IN JAPAN

被引：45

作者：

KATO, H

HORAI, T

FURUSE, K

FUKUOKA, M

SUZUKI, S

HIKI, Y

ITO, Y

MIMURA, S

TENJIN, Y

HISAZUMI, H

HAYATA, Y

机构：

[1] CTR ADULT DIS,DEPT INTERNAL MED 4,HIGASHINARI KU,OSAKA 537,JAPAN

[2] NATL KINKI CENT HOSP CHEST DIS,DEPT INTERNAL MED,SAKAI 591,JAPAN

[3] OSAKA PREFECTURAL HABIKINO HOSP,DEPT INTERNAL MED 2,HABIKINO 583,JAPAN

[4] TOKYO WOMENS MED COLL,INST GASTROENTEROL,DEPT ENDOSCOPY,SHINJUKU KU,TOKYO 162,JAPAN

[5] KITASATO UNIV,SCH MED,DEPT SURG,SAGAMIHARA,KANAGAWA 228,JAPAN

[6] AICHI CANC CTR,DEPT ENDOSCOPY,CHIKUSA KU,NAGOYA,AICHI 464,JAPAN

[7] CTR ADULT DIS,DEPT INTERNAL MED 3,HIGASHINARI KU,OSAKA 537,JAPAN

[8] KYOUNDO HOSP,SASAKI INST,DEPT GYNECOL,CHIYODA KU,TOKYO 101,JAPAN

[9] KANAZAWA UNIV,SCH MED,DEPT UROL,KANAZAWA,ISHIKAWA 920,JAPAN

[10] TOKYO MED COLL,CTR CANC,SHINJUKU KU,TOKYO 160,JAPAN

来源：

JAPANESE JOURNAL OF CANCER RESEARCH | 1993年 / 84卷 / 11期

关键词：

PHOTODYNAMIC THERAPY; PHOTOFRIN; ARGON DYE LASER; EXCIMER DYE LASER;

D O I：

10.1111/j.1349-7006.1993.tb02823.x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Photodynamic therapy utilizing Photofrin has proven to be an effective modality that can be use in the treatment of a wide variety of solid tumors and luminal cancers. An argon pumped dye laser or excimer dye laser was used to deliver 630 nm tight via quartz fibers passed through the biopsy channel subsequent to i.v. injection of photosensitizer. In this study, 64 patients with superficial cancers were treated in this manner but only 58 patients, including 21 with roentgenographically occult lung cancer, 8 with stage I lung cancer, 5 with esophageal cancer, 12 with gastric cancer, 8 with cervical cancer and 4 with bladder cancer were evaluable. Complete remission was obtained in 48 out of 58 cases (82.8%). There was no serious complication except skin photosensitivity, which was seen in 13 patients. We conclude that photodynamic therapy is efficacious in the treatment of superficial cancers where complete remission may be achieved.

引用

页码：1209 / 1214

页数：6

共 17 条

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