UNUSUAL DEFICIENCY OF THE MODIFIED PURINE BASE QUEUINE IN TRANSFER-RIBONUCLEIC-ACID FROM THE HUMAN PLACENTA AS TESTED BY ENZYMATIC ASSAY

被引：5

作者：

BARANOWSKI, W

TOMASZEWSKI, J

KEITH, G

机构：

[1] UNIV STRASBOURG 1, F-67070 STRASBOURG, FRANCE

[2] CNRS, INST BIOL MOLEC & CELLULAIRE, UNITE STRUCT MACROMOLEC BIOL & MECAN RECONNAISSANC, STRASBOURG, FRANCE

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1993年 / 169卷 / 03期

关键词：

QUEUINE; TRANSFER RIBONUCLEIC ACID; HUMAN PLACENTA;

D O I：

10.1016/0002-9378(93)90626-T

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Transfer ribonucleic acid from rapidly growing tissues, particularly from neoplasia, is partially deficient in queuine, a highly modified transfer ribonucleic acid constituent. By means of an enzymatic assay we also found a queuine deficiency (14%) in human placenta transfer ribonucleic acid despite its high concentrations in the amniotic fluid. Proposed cause and significance of the results are discussed.

引用

页码：581 / 582

页数：2