2,6-DI-TERT-BUTYL-4-METHYLENE-2,5-CYCLOHEXADIENONE - HEPATIC METABOLITE OF BUTYLATED HYDROXYTOLUENE IN RATS

被引：43

作者：

TAKAHASHI, O

HIRAGA, K

机构：

[1] Department of Toxicology, Tokyo Metropolitan Research Lahoratory of Puhlic Health, Shinjuku-ku, Tokyo, 1611, 24-1

来源：

FOOD AND COSMETICS TOXICOLOGY | 1979年 / 17卷 / 05期

关键词：

D O I：

10.1016/0015-6264(79)90003-8

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two metabolites of butylated hydroxytoluene were isolated from the livers of orally treated male rats. The major metabolite was identified as 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone, by gas chromatography and mass spectroscopy and by reduction with lithium aluminium hydride. Only non-conjugated unchanged BHT was identified in samples of lung, kidney, pancreas, brain and adipose tissue from these rats. © 1971.

引用

页码：451 / 454

页数：4

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